Chinese twin study: simian crease passes inter- & intra-observer agreement test!

**Martijn (admin)** on Thu Sep 16, 2010 2:43 pm

Earlier this year a Chinese study revealed that the 'simian crease' has passed a test focussed on inter- and intra-observer agreement. This result implicates that the 'simian crease' meets an important requirement for any application in hand diagnostics!

http://www.ncbi.nlm.nih.gov/pubmed/20158312

SUMMARY:

Physical features observation: is it repeatable in zygosity determination of Chinese adult twins?

Twin Res Hum Genet.
2010 Feb;13(1):96-100.

Gao W, Li L, Cao W, Zhan S, Zhao Y, Wang H, Hu Y.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.

This study reports on the inter- and intrarater reliability of physical features observation. Study subjects were 176 Chinese adult persons, consisting of 89 males and 87 females. Three trained research assistants responded simultaneously and respectively to 12 items regarding the subject's physical features including 'hair', 'Mongoloid folds', left and right 'ear lobes', 'earwax', 'nostril shape', 'tongue rolling', left and right 'hitchhiker's thumb', 'mid-digital hair' and left and right 'simian crease' at the moment of interview. And 14 days later, these subjects received the same observation once again. The results showed that the inter- and intra-observer agreements of 'hair', 'earwax', 'tongue rolling', 'mid-digital hair' and 'simian crease' were almost perfect with most kappa (kappa) coefficients >or= .80, while 'Mongoloid fold' and 'nostril shape' showed poor inter-observer agreement and 'nostril shape' showed poor intra-observer agreement (kappa < .40). Two other physical features, 'hitchhiker's thumb' and 'ear lobes' showed moderate inter-observer agreement and three features, 'hitchhiker's thumb', 'ear lobes' and 'Mongoloid fold', showed moderate intra-observer agreement (.40<or= kappa <.80). In conclusion, this study suggests that as far as reliability is concerned, the five features which were 'hair', 'earwax', 'tongue rolling', 'mid-digital hair' and 'simian crease' could be considered in zygosity determination of Chinese adult twins, while the two features, 'Mongoloid fold' and 'nostril shape', should be abandoned.

PMID: 20158312 [PubMed - indexed for MEDLINE]

**asif amin** on Thu Sep 30, 2010 6:25 pm

Related to this topic, I have some palm prints of Mongoloids, it is taken from M.A Malik's book " The new horizon in palmistry".

Chinese twin study: simian crease passes inter- & intra-observer agreement test! A710

Chinese twin study: simian crease passes inter- & intra-observer agreement test! A710

**jeanette** on Thu Sep 30, 2010 7:55 pm

Hi Asif,
Thanks for posting all that. You send a lot of great information.
Jeanette.

**Martijn (admin)** on Thu Sep 30, 2010 10:21 pm

asif amin wrote:Related to this topic, I have some palm prints of Mongoloids, it is taken from M.A Malik's book " The new horizon in palmistry".

Thanks Asif!!

Thumbs up!

By the way, for those who are not yet aware of the 'vocabulary'... the words mongoloid refers to people who have a genetic disorder named 'trisomy 21', which is better known as Down's syndrome.

On my website I present HIGH RESOLUTION examples of (both) hands of two people who both have Down syndrome - including a very detailed analyses of all related hand characteristics, see:
http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm

Chinese twin study: simian crease passes inter- & intra-observer agreement test! Down-syndrome-1-small

Chinese twin study: simian crease passes inter- & intra-observer agreement test! Down-syndrome-1-small

Chinese twin study: simian crease passes inter- & intra-observer agreement test! Down-syndrome-2-small

**asif amin** on Mon Oct 04, 2010 6:29 pm

Some links about Down Syndrome ( Mongoloids ). It is easy to see website rather than I post all material it covers more space of page (thread)

http://en.wikipedia.org/wiki/Down_syndrome

http://medical-dictionary.thefreedictionary.com/Mongoloid+idiot

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Chinese twin study: simian crease passes inter- & intra-observer agreement test!

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